Bhargav

· 13 Nov 2021

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What is normal creatinine level?

The kidneys maintain an average blood creatinine level. Creatinine is a good indicator of kidney function, according to research. A high creatinine level is a sign of kidney disease or impaired kidney function.

The creatinine level in the blood will rise if the kidneys cannot clear creatinine from the blood. Increased levels of creatinine are therefore a warning sign that the kidneys may be malfunctioning or failing. Because of this, creatinine levels are routinely checked during standard blood tests.

Calculating how much creatinine is excreted from the body by the kidneys provides a more accurate measure of kidney function. This is known as creatinine clearance, and it measures how quickly the kidneys can remove creatinine from the bloodstream (glomerular filtration rate, or GFR). There are two ways to measure creatinine clearance. Serum (blood) creatinine level, patient weight, and age can be used to calculate (estimate) it. Serum creatinine level divided by 72 times patient's age divided by kg/dL is the formula for determining a patient's risk of developing kidney disease. Alternatively, a 24-hour urine sample and a blood sample can be used to measure creatinine clearance. Both the urine and blood levels of creatinine are measured and compared. Creatinine clearance in healthy women ranges from 88 to 128 mL/min, and in men, it ranges from 97 to 137 mL/min (normal levels may vary slightly between labs).

An elevated blood urea nitrogen (BUN) level is a further sign that the kidneys are working correctly. As a byproduct of metabolism, urea can build up if kidney function is impaired. Comparing the creatinine level alone with the BUN-to-creatinine ratio can provide more information about kidney function and its potential underlying cause. Dehydration also raises BUN levels.

Prostate cancer has been linked to elevated creatinine levels in adult males; in infants, this has been linked to bacteremia.

What is the usual range of creatinine levels in the human bloodstream?
Adult males' creatinine levels typically range between 0.6 and 1.2 milligrams per deciliter (dL), while females' ranges are between 0.5 and 1.1 milligrams per deciliter (dL). A deciliter is a unit of volume equal to one-tenth of a liter, and milligrams are units of weight equal to one-thousandths of a gram.

Creatinine levels that are considered high are defined as what?
•    An average level for a person with only one kidney is around 1.8 or 1.9.
•    It is possible to have severe kidney disease if creatinine levels reach 2.0 in babies and 5.0 in adults.
•    The BUN, creatinine level, potassium level, and how much fluid the patient is retaining all play a role in determining the need for a dialysis machine to remove wastes from the blood.

What are the side effects of high creatinine levels, and how do they manifest?

One of the most common symptoms of kidney failure (renal insufficiency) is dizziness. Creatine levels in the blood do not appear to be correlated with them.

Some people may discover severe kidney disease and elevated creatinine on routine bloodwork even though they have no symptoms.

The symptoms of kidney failure can vary from person to person, depending on the cause of the problem, and include: o feeling dehydrated, o exhaustion, o swelling (edema), o breathlessness, o confusion, or any number of other nonspecific symptoms (for example, nausea, vomiting, neuropathy, and dry skin).

Creatinine levels in the blood can be elevated for a variety of reasons.

•    The creatinine level in the blood can rise if the kidneys are unable to function correctly. Consider whether or not the kidney dysfunction (kidney failure, azotemia) process has been ongoing for some time. It may be easier to treat and reverse recent elevations.
•    High blood pressure and
•    Diabetes is the most common cause of long-term (chronic) kidney disease in adults.
•    Certain medications (such as Cimetidine [Bactrim]) can cause abnormally high creatinine levels.
•    After ingesting a large amount of meat, serum creatinine levels may rise for a short period.  
•    Kidney infections, rhabdomyolysis (abnormal muscle breakdown), and urinary tract obstruction may also cause a rise in creatinine.

Individuals with low or high levels of blood creatinine can be identified.
The creatinine levels in the blood of muscular young or middle-aged adults may be higher than the norm for the general population. The creatinine levels in the blood of elderly persons may be lower than the norm. Adults with malnutrition, severe weight loss, and long-term illnesses may have a creatinine level lower than expected for their age because muscle mass decreases over time. Infants have normal levels of about 0.2 or more, depending on their muscle development.

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#kidney
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#creatinine