Longo is the founder and private shareholder of L-Nutra L-Nutra; the company's nutritional products are used in studies of the "longevity diet". The co-author is also the founder of a company that sells "quick imitation" meal kits and diet plans designed to offer the benefits of fasting through strict calorie restriction, but with the option of small portions of certain foods.
Benefits
This emphasis on the need to demonstrate benefits through data is why the world's authority on dietary interventions believes in a fasting-mimicking diet. The development of the rapid mimic diet led the world authority on dietary intervention and his team to years of research, but gained widespread attention after a 2015 mouse study showed compelling results in multisystem regeneration, improved cognition and health.
Longevity Institute
A 2015 study by the Longevity Institute, also conducted on mice, found that a four-day fasting-mimicking diet increased lifespan, reduced visceral fat, reduced cancer rates, and rejuvenated the immune system. A fasting-mimicking diet promotes regeneration and reduces symptoms of autoimmunity and multiple sclerosis. Daily fasting improves the health and survival of male mice, regardless of diet composition and calorie content.
Mice Study
Another study in mice also shows that weekday fasting helps prevent weight gain. Researchers say intermittent fasting for several days or following a fasting-mimicking diet may also be helpful. A 5-day fasting or fasting cycle every 3-4 months may also help reduce insulin resistance, blood pressure, and other risk factors in people at increased risk for the disease.
Epidemiological
Epidemiological studies have shown that prolonged and persistent overnight fasting, similar to a time-restricted diet, can significantly reduce the risk of chronic disease. These data suggest that prolonged fasting or meal timing, even if it does not affect weight, may provide health benefits for some people.
Health
In addition to exploring which foods might be the best, a new study looked at how meal timing affects health and longevity. Researchers analyzed hundreds of studies to determine the diet that optimizes human health and longevity. A growing body of evidence suggests that optimal nutrition may depend on an interplay of health factors, including age, gender, and genetics.
Walter Longo
According to researchers at USC Leonard Davis School of Gerontology Professor Walter Longo and University of Gerontology's Rosalind M. Anderson Diet may be best for longevity. health care. Although fasting and other diets are often associated with weight loss, the coauthors believe they are also important for long-term health. Researchers have found that diets low in animal protein and high in complex carbohydrates, including periods of fasting, are most beneficial for long-term health and longevity. Longo found that mice eating a lean diet had many health benefits.
Fasting Mimicking
The fasting-mimicking diet was actually the result of years of animal research to try and figure out how much Dr. Walter Longo could add to someone's diet before losing the fasting effect, and what ingredients to include. We have developed a diet that mimics almost any fast. Longo set out to develop a minimum calorie diet that would provide the nutrition needed by cancer patients but also offer the benefits of fasting.
Ambra Ditonno
To develop a fasting diet that people actually like to eat, Longo turned to Ambra Ditonno, an old friend who ran a famous Italian café in Hollywood. The scientists focused on several types of fasting, including traditional intermittent fasting, which restricts food intake to a limited amount of time each day, and intermittent fasting, or mock fasting, which occurs only one or two days a month. "The macrobiotic diet is an evolution of those 'century-old diets,'" Longo explained, citing recommendations to limit food intake to 12 hours a day and practice short-term fasts several times a year. In an article containing a literature review published April 28 in the journal Cell, Longo and co-author Rosalyn Anderson of the University of Wisconsin describe the macrobiotic diet, an integrative approach based on research into all aspects of diet . , from food composition and calorie content to fasting duration and frequency.
Algal Oil Supplements
The diet includes additional ingredients—algal oil supplements, certain proteins, popular supplements like flaxseed, inulin, glycerin, and apple cider vinegar—that Longo says can improve health or make the body think it's starving. Fasting 3 to 4 times a year, with a greater emphasis on caloric restriction or narrowing the food intake window, may also be beneficial, as intermittent fasting also reduces high blood pressure, high cholesterol, and inflammation, all of which contribute to various chronic. Researchers. Small, short-term human studies have shown that intermittent fasting can reduce weight, belly fat, cholesterol and blood sugar levels, as well as proteins such as C-reactive protein and IGF-1 that have been linked to inflammatory diseases and cancer.
Broad benefits
The authors concluded that numerous clinical studies have demonstrated the broad benefits of intermittent fasting for many age-related conditions and diseases, including diabetes, cardiovascular disease, cancer, and neurological disorders. A study published Sept. 29 in the journal Nature shows how intermittent fasting works within cells to slow the aging process (at least in fruit flies), noting that in the absence of hunger Learn about the potential health benefits of fasting. For researchers at Columbia University, the role of time has become key to understanding the relationship between fasting and longevity.
Fasting every other day
Fasting every other day improves physiological and molecular markers of aging in healthy non-obese individuals. Intermittent fasting was not associated with the beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to damage caused by caloric intake.
Keywords
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